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| Wednesday 20 August, 2008 |
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CHIKUNGUNYA FEVER
Safety Precautions for Chikungunya Fever Casualties Standard Precautions defined by the 1996 CDC guidelines should be adopted for handling patients. Mosquito control should be practiced.
Synopsis of Agent Properties Causative organism: (Systematic name in 1997) Chikungunya virus Alternative names: Buggy Creek virus Alternative disease names: None
ICTV Acronym CHIKV Properties: Family: Togaviridae Genus: Alphavirus A positive-sense, single-stranded RNA virus. Click here for a detailed description of Alphaviruses Vector involvement: The disease is spread by culicine mosquitoes.
Key Diagnostic Tests. Sudden severe headache, chills, fever, joint and muscle pain are the commonest symptoms.
Detection of antigens or antibody to the agent in the blood (serology) ELISA is available An IgM capture ELISA is necessary to distinguish the disease from dengue fever. Differential Diagnosis Other disease or conditions that need to be eliminated Other infectious diseases Other problems Dengue fever None
Symptoms and effects.
After an incubation period of 3-12 days there is a sudden onset of flu-like symptoms including a severe headache, chills, fever (>40°C,104°F), joint pain, nausea and vomiting. The joints of the extermities in particular become swollen and painful to the touch. A rash may sometimes occur. Hemorrhage is rare and all but a few patients recover within 3-5 days. Some can suffer for joint pain for months. Children may display neurological symptoms.
Medical and Physical Countermeasures.
Vaccination (Immunoprophylaxis)
A vaccine is not available.
Specific Therapy
No specific therapies are available.
Supportive care
Symptoms are treated, e.g. with analgesics and anticonvulsants.
Decontamination The virus is killed by common disinfectants, moist heat and drying. The vector (a mosquito) also needs to be controlled with insecticides.
Agent Properties and Potential Uses
Chikungunya virus is highly infective and disabling but is not transmissible between people. It would most likely be dispensed as an aerosol or by the release of infected mosquitos. The disabling joint pain and fever, the lack of a suitable animal reservoir in Western countries and its lack of lethality make it a very "clean" weapon that could be used against key civilian installations. The name comes from the Swahili for "that which bends up" that is a reference to the positions that victims take to relieve the joint pain.
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